SERVICE UPDATE:

In accordance with Government guidance, all our laboratory based services are now closed, except for SARS-CoV-2/COVID-19 work.

However, all Bioinformatics activities are fully operational, and you can still contact us by email if you need advice on projects or quotes for future work.





Sequencing

We are skilled in delivering high-quality next-generation sequencing data from RNA and DNA samples, using Illumina NovaSeq and MiSeq platforms in addition to the Pacific Biosciences Sequel and the Oxford Nanopore PromethION. We also regularly carry out Sanger dideoxy sequencing, using AB3730 instruments

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Training

From introductory coding courses (Linux, R, Python) to advanced workshops on the latest bioinformatics tools (RNA-seq data analysis, metagenomics), we offer a wide range of courses equipping you with the skills you need to tackle your next genomic analysis.

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Bioinformatics

Bioinformatic analysis is at the heart of what we do, and our dedicated team of research informaticians is skilled in all aspects of next generation genomics and genetic analyses. We have an extensive, secure compute install for high-throughput data processing.

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Latest news

Service Update: COVID-19
SERVICE UPDATE: In accordance with Government guidance, all our laboratory based services are now closed. However, all Bioinformatics activities are fully operational, and...
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Gene study boosts bid to keep British bees safe from disease
Efforts to protect the UK's native honey bees could be helped by research that maps their entire genetic make-up. Experts also analysed the genetic profile of bacteria and...
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The Darwin Tree of Life Project
A global effort has been officially launched to sequence all living organisms on Earth including animal, plant, protozoan and fungal species. The project, known as the Earth...
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Publications

Selective miRNA Modulation Fails to Activate HIV Replication in In Vitro Latency Models López-Huertas, M. R., Morín, M., Madrid-Elena, N., Gutiérrez, C., Jiménez-Tormo, L., Santoyo, J., Sanz-Rodríguez, F., Moreno Pelayo, M. Á., Bermejo, L. G. & Moreno, S. 2019 In: Molecular therapy. Nucleic acids p. 323-336 14 p. Custom text:
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Transcriptomics Analysis of Porcine Caudal Dorsal Root Ganglia in Tail Amputated Pigs Shows Long-Term Effects on Many Pain-Associated Genes Sandercock, D. A., Barnett, M. W., Coe, J. E., Downing, A. C., Nirmal, A. J., Di Giminiani, P., Edwards, S. A. & Freeman, T. C. 2019 In: Frontiers in Veterinary Science Custom text:
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Whole Genome Sequencing of Giant Schnauzer Dogs with Progressive Retinal Atrophy Establishes NECAP1 as a Novel Candidate Gene for Retinal Degeneration Hitti, R. J., Oliver, J. A. C., Schofield, E. C., Bauer, A., Kaukonen, M., Forman, O. P., Leeb, T., Lohi, H., Burmeister, L. M., Sargan, D. & Mellersh, C. S. 2019 In: Genes Custom text:
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Adaptive evolution Is common in rapid evolutionary radiations Nevado, B., Wong, E. L., Osborne, O. G. & Filatov, D. A. 2019 In: Current Biology Custom text:
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Lack of long-term acclimation in Antarctic encrusting species suggests vulnerability to warming Clark, M. S., Villota Nieva, L., Hoffman, J. I., Davies, A. J., Trivedi, U. H., Turner, F., Ashton, G. V., Peck, L. S. & Trivedi, U. 2019 In: Nature Communications Custom text:
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