Sequencing

We are skilled in delivering high-quality next-generation sequencing data from RNA and DNA samples, using Illumina NovaSeq, HiSeq X and MiSeq platforms in addition to the Pacific Biosciences Sequel. We also regularly carry out Sanger dideoxy sequencing, using AB3730 instruments

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Clinical Genomics WGS

Whole Genome Sequencing of samples using the Illumina HiSeq X platform produces high quality data at an unprecedented speed and low cost. Laboratory automation using Illumina SeqLab platform allows very high efficiency and low variability.

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Genotyping-Arrays

High-density genotyping of pedigrees and populations, and microarray analyses of expression, binding and copy number variation are mainstays of genetic and genomic analysis. We offer genotyping and microarray gene expression analyses using Illumina and Affymetrix platforms.

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Bioinformatics

Bioinformatic analysis is at the heart of what we do, and our dedicated team of research informaticians is skilled in all aspects of next generation genomics and genetic analyses. We have an extensive, secure compute install for high-throughput data processing.

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Latest news

A global effort has been officially launched to sequence all living organisms on Earth including animal, plant, protozoan and fungal species. The project, known as the Earth...
A limited number of spaces remain available for our Introduction to Python for Biologists workshop (22 - 26 October 2018). Further course information can be found here. ...
To view our Summer 2018 newsletter, click the image below:  
We have a limited number of remaining places, on a first come first served basis, to our Linux for Genomics and Introduction to RNAseq Data Analysis ...
We now offer registration, on a first come first served basis, to our Linux for Genomics, Introduction to RNAseq Data Analysis, and Introduction to Python for...

Publications

Optimised isolation method for RNA extraction suitable for RNA sequencing from feline teeth collected in a clinical setting and at post mortem Lee, S., Trivedi, U., Johnson, C., Farquharson, C. & Bergkvist, G. 2018 In: Veterinary Research Communications Custom text:
Metabolic Remodeling during Liver Regeneration Caldez, M. J., Van Hul, N., Koh, H. W. L., Teo, X. Q., Fan, J. J., Tan, P. Y., Dewhurst, M. R., Too, P. G., Talib, S. Z. A., Chiang, B. E., Stünkel, W., Yu, H., Lee, P., Fuhrer, T., Choi, H., Björklund, M. & Kaldis, P. 2018 In: Developmental Cell Custom text:
Comparative population genomics reveals key barriers to dispersal in Southern Ocean penguins Clucas, G. V., Younger, J. L., Kao, D., Emmerson, L., Southwell, C., Wienecke, B., Rogers, A. D., Bost, C., Miller, G. D., Polito, M. J., Lelliott, P., Handley, J., Crofts, S., Phillips, R. A., Dunn, M. J., Miller, K. J. & Hart, T. 2018 In: Molecular Ecology Custom text:
Bovine Staphylococcus aureus superantigens stimulate the entire T 2 cell repertoire of cattle. Wilson, G., Tuffs, S., Wee, B., Seo, K. S., Park, N., Connelley, T., Guinane, C. M., Morrison, W. & Fitzgerald, J. 2018 In: Infection and Immunity Custom text:
Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and reduced microglial activity Brown, S., Bush, S., Summers, K., Hume, D. & Lawrence, A. B. 2018 In: Behavioural Brain Research p. 6-15 Custom text:

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